Glucosamine Phosphate

What is Glucosamine Phosphate?

Glucosamine phosphate is part of an enzyme that helps facilitate a chemical reaction, the products of which help stimulate glucose metabolism and the process by which glucosamine is produced in the body. Glucosamine phosphate is essential for carbohydrate synthesis in the body, and a source of energy for a substance known as phophoenolpyruvate.

Glucosamine phosphate aids in sugar metabolism, assisting in conversion of carbohydrates and successful catalyzation of chemicals in the body during transport of carbohydrate sugars in various bio systems. Glucosamine phosphate is part of natural glucosamine in the body, part of the glutamate metabolic pathways, nucleotide metabolic pathways, and phosphotransferase systems or PTS enzymatic pathways in the body.

Aging and Body Deterioration

As with any metabolic system, with aging the body slows down. Metabolic systems deteriorate and begin to function less optimally. Chronic diseases, obesity, poor eating habits and poor health tend to affect the ability of the body to metabolize sugars and fats.

Glucosamine Supplementation

Supplementation with glucosamine may help correct metabolic imbalances and promote less inflammation in the body, which can affect glutamate metabolism, sugar metabolism and the PTS.

Glucosamine Phosphate Benefits

Glucosamine phosphate is helpful for reducing inflammation and improving the overall health and wellness of many body functions. Researchers have confirmed a link between the effects of glucosamine on connective tissue and cartilage, showing that glucosamine in many forms, including sulfate, hydrochloride, chitosan, and n-acetylglucosamine can help restore damaged tissues and improve synovial fluids. It stands to reason that supplementation with glucosamine may improve glucosamine phosphate enzymatic activity in the body as well. This may improve glutamate metabolism and carbohydrate metabolism.

Glucosamine Phosphate Side Effects

Research has shown relatively few side effects associated with consumption of glucosamine, although some studies suggest a link may exist between insulin resistance or glucose intolerance and glucosamine consumption. This link is weak however, and further studies are necessary to confirm whether a risk exists for patients with sugar metabolism problems.

Glucosamine has far fewer side effects than traditional treatment methods for inflammation, including less stomach problems and a reduced chance for hepatic toxicity.

Glucosamine is very beneficial, recommended by many researchers to improve glucosamine phosphate and improve carbohydrate metabolism thereby improving overall sugar and carbohydrate metabolic function, leading to decreased systemic inflammation throughout the body.

References:

Banda K; Gregg CJ; Chow R; Varki NM; Varki A. Metabolism of vertebrate amino sugars with N-glycolyl groups: mechanisms underlying gastrointestinal incorporation of the non-human sialic acid xeno-autoantigen N-glycolyneuraminic acid. J Biol Chem. 2012 Jun 12. Pub Med Available; http://www.ncbi.nlm.nih.gov/pubmed/22692204

Davidson, EA; Blumentha, HJ; Roseman S. Glucosamine 6-phosphate N-acetylase. Methods Enzymol. 9(1): 704-707. Available: http://www.sciencedirect.com/science/article/pii/0076687966091420

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